The VP4 peptide of Hepatitis A Virus (HAV) Ruptures Membranes

The VP 4 peptide of Hepatitis A Virus ( HAV ) Ruptures Membranes 2 Through Formation of Discrete Pores

Molecular Detection of Hepatitis A Virus in Urban Sewage in Isfahan, Iran

ABSTRACT            Background and Objectives: Hepatitis A virus (HAV) enters sewage through the stool of infected patients and contaminates freshwater and seawater. The aim of present study was quantitative molecular detection of HAV in raw and treated urban sewage samples from Isfahan, center of Iran.      &nbs...

Monitoring the Hepatitis A Virus in Oyster from Korea

Hepatitis A virus (HAV) causes many cases of oysteror clam-associated gastroenteritis in various countries. HAV was detected on oyster by RT-PCR in 19.6% (11/56) in Korea. The percentages of HAV-positive samples in 2011 and 2012 were 27.6% and 11.1%, respectively. Phylogenetic analysis revealed that several nucleotide sequences highly similar to those of HAVs isolated in this study. Phylogeneti...

فراوانی آنتی بادی ویروس هپاتیت A در مبتلایان هپاتیت B و C در ایران

Background: Superinfection of hepatitis A in chronic hepatitis B and C may worsen the course of disease. This study attempted to study frequency of hepatitis A virus antibodies in patients with hepatitis B and hepatitis C. Materials and methods: 115 hepatitis C and 56 hepatitis B patients who visited the Hepatitis Association of Hamedan province during 2004-2005 were enrolled. Hepatitis A viru...

Intrinsic signals for the assembly of hepatitis A virus particles. Role of structural proteins VP4 and 2A.

Capsid assembly is the final event of virus replication, and its understanding is pivotal for the design of empty capsid-based recombinant vaccines and drug delivery systems. Although the capsid structure of several members of the picornavirus family has been elucidated, little is known about the structural elements governing the assembly process that is tightly associated with proteolytic proc...